Kalakshar US

A Parkinson’s patient can now walk 6km (3.7 miles) thanks to an implant targeting the spinal cord. The Guardian reports that the man — 62-year-old “Marc” from Bordeaux, France — developed severe mobility impairments from the degenerative disease. “I practically could not walk anymore without falling frequently, several times a day,” he said in a press release announcing the breakthrough. “In some situations, such as entering a lift, I’d trample on the spot, as though I was frozen there, you might say.” Wearing the spinal implant allows him to walk “almost normally” as the research team eyes a full clinical trial.

Marc underwent a “precision neurosurgical procedure” two years ago at Lausanne University Hospital (CHUV), which helped facilitate the research. The surgery fitted him with an electrode field placed against his spinal cord and an electrical impulse generator under the skin of his abdomen. Although conventional Parkinson’s treatments often target brain regions affected by the loss of dopamine-producing neurons, this approach instead focuses on the spinal area associated with activating leg muscles for walking.

The procedure used a personalized map of Marc’s spinal cord, identifying the specific locations signaling leg movements. He wears a movement sensor on each leg that tells the implant he’s trying to walk; it then switches on and sends electrical impulses to the targeted spinal neurons, adapting to his movement in real-time.

“In response to precise stimulation of the lumbar spinal cord, I’ve observed for the first time remarkable improvements of gait deficits due to Parkinson’s disease,” project supervisor Jocelyne Bloch, professor and neurosurgeon at CHUV Lausanne University hospital, said in a webinar discussing the patient’s success. “I really believe that these results open realistic perspectives to develop a treatment.”

The patient says he could walk practically normally with the stimulation after several weeks of rehab. He now wears it for around eight hours daily, only turning it off when sleeping or lying down for a while. “I turn on the stimulation in the morning and I turn off in the evening,” he said. “This allows me to walk better and to stabilise. Right now, I’m not even afraid of the stairs anymore. Every Sunday I go to the lake, and I walk around 6 kilometres. It’s incredible.”

The researchers caution that there’s still a vast chasm between tailoring the approach to one person vs. optimizing it for wide-scale use. Co-leads Grégoire Courtine and Bloch are working on a commercial version of the neuroprosthetic in conjunction with Onward Medical. “Our ambition is to provide general access to this innovative technology to improve the quality of life of Parkinson’s patients significantly, all over the world,” they said.

Michael J. Fox (right) with Sting.

In the meantime, research on six new patients will continue in 2024. The team says a “generous donation” of $1 million from the Michael J. Fox Foundation for Parkinson’s Research is funding the upcoming work. In 2021, the actor’s organization announced it had contributed over $1.5 billion to Parkinson’s research.

This article originally appeared on Engadget at https://www.engadget.com/spinal-implant-allows-parkinsons-patient-to-walk-for-miles-193637427.html?src=rss 

At least 15 visitors at Yuga Labs’ Apefest, a celebration of the marvels of Bored Ape Yacht Club NFTs, may have experienced serious eye injuries. Bloomberg reports that multiple people attending the NFT event in Hong Kong last weekend say they experienced vision problems, which they suspect stemmed from the event’s stage lighting. Some of the attendees claim doctors subsequently diagnosed them with photokeratitis (aka “welder’s eye”), caused by exposure to ultraviolet (UV) light.

“Woke up in the middle of the night after Apefest with so much pain in my eyes that I had to go to the hospital,” the user Crypto June posted on X (via Coin Telegraph). “Doctor told me it was due to the UV from stage lights.” User @docwagmi suspected that the “ape friends” reporting problems appeared to have been “up close with us front stage.” 

The event’s elaborately stylized bathrooms.

Meanwhile, Adrian Zduńczyk wrote on X, “To all my friends who suffer now: go get your eyes checked. You’ve likely most literally got your eyes burnt with UV like I did, which requires medications, eye drops, eye protection, antibiotics and specialist care. Don’t ignore this health hazard. Without proper treatment, it may cause long lasting vision impairment and other serious damage.” Zduńczyk wrote that seeking medical attention quickly appears to have spared him long-term damage. “My vision was tested as close to perfect with no serious cornea damage, luckily.”

Yuga Labs briefly addressed the issue on X, saying it’s “aware of the eye-related issues that affected some of the attendees of ApeFest,” while claiming it’s “proactively reaching out to individuals since yesterday to try and find the potential root causes.” The company downplayed the number of people reporting issues, adding, “Based on our estimates, we believe that much less than 1% of those attending and working the event had these symptoms.” The NFT company advised attendees experiencing symptoms to “seek medical attention just in case.”

X users seemed none too pleased with Yuga Labs’ PR response:

The potentially dangerous incident echoes one in 2017 when attendees of a HypeBeast party reported eye damage. The event’s DJ later reported that the lighting contractor used Philips bulbs that emit UV-C, often used as a disinfectant.

This article originally appeared on Engadget at https://www.engadget.com/blind-apes-nft-party-leads-to-reports-of-welders-eye-from-stage-lighting-173746164.html?src=rss 

Probe meat thermometers are insanely helpful whether you’re cooking indoors or out. They help ensure you don’t serve your family and friends undercooked chicken or an overcooked steak. While most of them use wired probes attached to some type of display or hub, Meater’s probes are completely wireless. This means you don’t have to dodge a cable when flipping or moving things around the grill. They’re also easier to use when wrapping large cuts like pork shoulders or brisket.

With two models under its belt, the Traeger-owned company is debuting its latest version today: the Meater 2 Plus. While the device may look awfully similar to Meater’s previous cooking gadgets and it still uses the charger as a Bluetooth range booster, there are some significant upgrades here. The company has installed additional sensors for more precise temperature readings, while also increasing heat resistance and overall durability. It has managed to do this without drastically increasing the price, too.

The biggest change for the Meater 2 Plus is on the inside. The company has added four more internal temperature sensors for a total of five. There’s also still the ambient temperature sensor on the opposite end to keep tabs on grill temps while you’re cooking. Meater says the five internal sensors offer “the real core temperature of the meat,” which it says can help reduce any subpar results due to an error in probe placement (the app helps with that, too). All five can measure temps down to a tenth of a degree with an accuracy that’s within half a degree.

The Meater app displays the lowest temperature of the five sensors in the main view of the app and goes by that for any targets you may have set. Additionally, you can see the real-time temps of all five sensors by tapping on the one being displayed. As it did before, the company’s mobile app offers guidance on target temperatures based on the doneness level you desire. There are lots of options for different types and cuts of meat, but you can also go full manual mode if you’re doing something like reheating leftovers or know exactly what you want. Either way, the app calculates estimated finishing time based on internal and ambient temperatures. It also warns you when there’s five minutes left, when you hit the target and when the required rest time (if any) is over.

Meater also added a new Master Class feature to its app that will offer over 50 video courses that teach cooking techniques like two-zone BBQ, reverse searing and more. Step-by-step demos will include ingredient and tool checklists for easy shopping. There will also be detailed written instructions so you’re not constantly swiping back through videos. Meater says this is just the initial batch and it plans to release new classes on a weekly basis.

The other big physical updates are improved heat resistance and durability. First, the Meater 2 Plus can withstand open flames at temperatures up to 932 degrees Fahrenheit (500 Celsius). This allows you to keep the probe in place while you sear. What’s more, the Meater app will warn you when the device is getting too hot.

That’s over 400 degrees hotter than the max temperature rating of the Meater Plus (527 degrees Fahrenheit). Plus, much of the competition, like ThermoPro’s TempSpike, can only handle just under 600 degrees. The Meater 2 Plus also has nine degrees more when it comes to the hottest internal temperature, now topping out at 221 degrees. The Meater 2 Plus is fully waterproof, so you can use it to deep fry or sous vide, as well. And when you’re done, you can just pop it in the dishwasher. I’ve done it several times and it’s still working just fine.

The temperature and waterproof upgrades are made possible by a new full-metal, stainless steel probe design. The Meater 2 Plus is 30 percent slimmer than the Meater Plus and a new Zirconia ceramic band allows the Bluetooth signal to radiate from the device. Thanks to a “high-performance antenna” and “optimized RF design” specifically tuned for high heat, the Meater 2 Plus offers an expanded range of up to 250 feet. That’s up from 165 feet on the previous model. The company says the new version can technically achieve 2,500 feet, but that requires a direct line of sight and no RF interference.

Most of our backyards won’t accommodate that, and you’re going to walk into the house to grab a beer at some point. In my tests, I was able to venture from my deck all the way to the mailbox on the street without losing connection. Like other Meater products, the 2 Plus works with Meater Link for Wi-Fi and Meater Cloud, providing unlimited range, though you’ll need to connect the Meater 2 Plus to another phone, tablet or laptop for these features.

Meater also improved battery life and charging efficiency. The Meater 2 Plus can be recharged for up to two years with one AAA battery, doubling the longevity of the previous model which the company rated at 100 charges. A fully charged probe will still last over 24 hours before you’ll need to dock it, unchanged from the Meater Plus. However, the Meater 2 Plus charges to 50 percent in only 15 minutes, enough for a 12-hour low-and-slow barbeque session. And as the company points out, you’ll never have to worry about charging if you keep the probe docked when it’s not in use.

I’ve tested the Meater 2 Plus for three cooks so far and I’ve been impressed with the performance for all of them. It’s completely wild to me to be able to throw this thing in the dishwasher instead of spending several minutes scrubbing the probe like I typically have to for all of my wired accessories. Of course, the highlight is the increased precision, which gives you a more detailed look at what’s going on during your cook. It was especially handy while smoking a turkey breast, allowing me to make sure the center was safe to eat while monitoring the rest to make sure it didn’t get too far past the coveted 165-degree mark. I also had no issues with high-heat use, though most of my testing was sub-350 degrees and primarily low-and-slow smoking. Besides turkey, I also used it for Over the Top Chili, smoked meatloaf and reheating leftovers.

The Meater 2 Plus is available now on the company’s website for $119.95. That’s $10-$20 more than the Meater Plus, depending on your wood preference for the charger on that previous model.

This article originally appeared on Engadget at https://www.engadget.com/meater-2-plus-review-a-more-precise-and-durable-wireless-meat-thermometer-160039734.html?src=rss